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The Effect That Genotyping Errors Have on the Robustness of Common Linkage-Disequilibrium Measures

โœ Scribed by Joshua M. Akey; Kun Zhang; Momiao Xiong; Peter Doris; Li Jin


Book ID
117853624
Publisher
American Society of Human Genetics
Year
2001
Tongue
English
Weight
940 KB
Volume
68
Category
Article
ISSN
0002-9297

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## Abstract Because most multipoint linkage analysis programs currently assume linkage equilibrium between markers when inferring parental haplotypes, ignoring linkage disequilibrium (LD) may inflate the Type I error rate. We investigated the effect of LD on the Type I error rate and power of nonpa