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The effect on renal structure and function of late-life-introduced caloric restriction (CR) in rats

✍ Scribed by R. Podkowka-Sieczka; K. Wieczorowska-Tobis; Z. I. Niemir; A. Styszynski; A. Breborowicz; D. G. Oreopoulos

Publisher
Springer Netherlands
Year
2008
Tongue
English
Weight
275 KB
Volume
41
Category
Article
ISSN
0301-1623

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## Abstract In __C. elegans,__ insulin‐like hormone signal pathway plays a significant role in longevity. In particular, __daf‐16__ gene product is indispensable factor for this lifespan‐extension. This signal pathway is critical for dauer formation, which is a similar state to hibernation in mamma