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The effect of β-cyclodextrin on the solubility and dissolution rate of meloxicam and investigation of the driving force for complexation using molecular modeling

✍ Scribed by Aiman A. Obaidat; Rasha A. Khanfar; Mohammad N. Khawam

Publisher: Springer Netherlands
Year: 2008
Tongue: English
Weight: 340 KB
Volume: 63
Category: Article
ISSN: 0923-0750
DOI: 10.1007/s10847-008-9517-2

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Cyclodextrins are a group of cyclic oligosaccharides with a ring, basket-like structure. These compounds are able to include several kinds of molecules into their internal cavity, leading to important modiÐcations of the properties of the guest compound. The interaction between b-cyclodextrin and t