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The effect of tumour burden in human leukaemia bearing SCID mice on immunotoxin therapy outcome

✍ Scribed by J.K. Turner; D.J. Flavell; J.A. Kohler; A. Noss; S.U. Flavell


Book ID
108473224
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
158 KB
Volume
8
Category
Article
ISSN
1433-2981

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The CD19+ CD38+ human Burkitt's lymphoma cell line Ramos grows aggressively when injected intravenously (i.v.) into severe combined immunodeficient (SCID) mice, killing 100% of animals within a 3 3 4 2 day period with widely disseminated disease. Treatment commencing 7 days after i.v. injection of R