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The effect of Triton and diphenylylethylacetic acid on cholesterol and fatty acid biosynthesis in isolated perfused liver

✍ Scribed by S. Garattini; P. Paoletti; R. Paoletti

Book ID
112703754
Publisher
Springer
Year
1959
Tongue
English
Weight
287 KB
Volume
15
Category
Article
ISSN
1420-682X

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Diltiazem inhibits fatty acid oxidation
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The eects of diltiazem on fatty acid metabolism were measured in the isolated perfused rat liver and in isolated mitochondria. In the perfused rat liver diltiazem inhibited oxygen uptake and ketogenesis from endogenous substrates. Ketogenesis from exogenously supplied palmitate was also inhibited. T