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The Effect of Triterpenes on the Excretion of Sodium and Potassium by Rats

✍ Scribed by Wenzel, Duane G. ;Koffj, Gilbert Y.

Publisher
Elsevier
Year
1956
Weight
184 KB
Volume
45
Category
Article
ISSN
0095-9553

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✦ Synopsis

The acetates of ursolic acid, oleanolic acid, glycyrrhetinic acid, lu eol, and lurenol were administered subcutaneously to adrenalectomized rats and tgeir effect on the excretion of sodium and potassium determined. Ursolic acid acetate induced significant sodiun retention at 3 mg. per rat. Potassium excretion was not d e c t e d .

EVERAL TRITERPENES have been tested and S found to be devoid of hormonal action as evaluated by the cold stress test, glycogen deposition, and uterine or prostate weight gain (1). Glycyrrhetinic acid was found t o influence sodium

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