Monitoring of indices of haematological, renal and hepatic toxicity in rats after a single i.v. bolus of methotrexate has shown that they vary with the time of day at which the drug is administered. Maximum toxicity occurs after administration at 0600 h. Further experimentation has shown that the am
β¦ LIBER β¦
The effect of timing of a single injection on the toxicity of methotrexate in the rat
β Scribed by Judie English; G. Wynne Aherne; Vincent Marks
- Publisher
- Springer
- Year
- 1982
- Tongue
- English
- Weight
- 358 KB
- Volume
- 9
- Category
- Article
- ISSN
- 0344-5704
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