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The effect of three rad genes on survival, inter- and intragenic mitotic recombination in Saccharomyces

โœ Scribed by Kowalski, Susanne ;Laskowski, Wolfgang

Publisher
Springer
Year
1975
Tongue
English
Weight
626 KB
Volume
136
Category
Article
ISSN
0026-8925

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โœฆ Synopsis

The effect of UV irradiation on the survival, inter- and intragenic mitotic recombination of 3 diploid UV sensitive Saccharomyces mutants was studied and compared with the wild type RAD. These strains, homozygous for either the RAD, r1s rad 9-4, or rad 2-20 gene, have DRF values for survival of 1:1.6:3:20.6 respectively, at LD1. Their recombination behaviour is not correlated to their survival characteristics. The RAD, r1s, and rad 2-20 strains showed UV induced mitotic inter- and intragenic recombinants; the induction in the r1s diploid is ca. 100 times greater for both the inter- and intragenic recombinants than in the RAD strain. The rad 9-4 diploid produced no UV induced mitotic recombinants whatsoever, and is therefore considered to be a rec- mutation.

๐Ÿ“œ SIMILAR VOLUMES

The effects of three rad genes on UV ind
The effects of three rad genes on UV induced mutation rates in haploid and diploid Saccharomyces cells
โœ Eckardt, Friederike ;Kowalski, Susanne ;Laskowski, Wolfgang ๐Ÿ“‚ Article ๐Ÿ“… 1975 ๐Ÿ› Springer ๐ŸŒ English โš– 743 KB

Effects of the rad 2-20, rad 9-4, r1s, and the corresponding wild type RAD alleles in haploid and homozygous diploid Saccharomyces strains on UV induced mutation rates from adenine, lysine and histidine dependence to independence are reported. The UV induced mutation rates were similar for the RAD,