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The effect of the pyrrolizidine alkaloid integerrimine on the chromosomes of mouse bone marrow cells

โœ Scribed by M.C. Gimmler-Luz; B. Erdtmann; R.A. Balbueno


Book ID
119093409
Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
615 KB
Volume
241
Category
Article
ISSN
0165-1218

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## Abstract Chromosome studies were performed on bone marrow aspirates from 15 patients treated with azathioprine. In most patients the immunosuppressive therapy produced structural changes of the chromosome complement. The structural chromosome aberrations disappeared after cessation of therapy. I