## Abstract We investigated the influence of the alkyltransferases (ATases) encoded by the __ada__ and __ogt__ genes of __Escherichia coli__ on the mutational specificity of alkylating agents. A new mutational assay for selection of __supF^β^__ mutations in shuttleβvector plasmids was used. Treatin
β¦ LIBER β¦
The effect of the Primary Structure of DNA on Induction of Mutations by Alkylating Agents
β Scribed by I. B. Rogozin; V. B. Berikov; E. A. Vasunina; O. I. Sinitsina
- Book ID
- 110351103
- Publisher
- SP MAIK Nauka/Interperiodica
- Year
- 2001
- Tongue
- English
- Weight
- 51 KB
- Volume
- 37
- Category
- Article
- ISSN
- 1022-7954
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## Abstract The alkylating agent methylmethanesulfonate (MMS) activates the cβjun Nβterminal kinase (JNK)/stressβactivated protein kinase (SAPK) and the p38 mitogenβactivated protein kinase (p38MAPK) pathways via different mechanisms of action. Activation of p38MAPK by MMS involves the pp125 focal