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The effect of the dopamine agonist pergolide on tyrosine hydroxylase activity in rat striatal and limbic miniprisms in vitro: A model for the dopamine autoreceptor?

✍ Scribed by Arnold G. Vulto; Christopher J. Fowler


Book ID
112343005
Publisher
Springer-Verlag
Year
1986
Tongue
English
Weight
595 KB
Volume
333
Category
Article
ISSN
0028-1298

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## Abstract Sixty percent of the dopamine β‐hydroxylase (DBH) (EC 1.14.2.1) activity in rat brain was found to be bound to membrane fractions. The additions of Triton X‐100 solubilized DBH completely and permitted the estimated of the total enzyme activity. In homogenates the DBH could be detected