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The effect of the cyclin D1 (CCND1) A870G polymorphism on colorectal cancer risk is modified by glutathione-S-transferase polymorphisms and isothiocyanate intake in the Singapore Chinese Health Study

✍ Scribed by Probst-Hensch, N. M.; Sun, C.-L.; Berg, D. V. D.; Ceschi, M.; Koh, W.-P.; Yu, M. C.


Book ID
121791277
Publisher
Oxford University Press
Year
2006
Tongue
English
Weight
105 KB
Volume
27
Category
Article
ISSN
0143-3334

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## Abstract Cyclin D1 (CCND1) and E‐cadherin (CDH1) have been shown to be important genes of the β‐catenin/LEF pathway that is involved in colorectal carcinogenesis. However, epidemiological studies on relationship between genetic variants of these two genes and colorectal cancer (CRC) have shown i