The antipsoriatic drug metabolite etreti
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K. Punnonen; T. Puustinen; C. T. JansΓ©n
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Article
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1988
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Springer-Verlag
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English
β 535 KB
We have studied the effect of etretin (Ro 10-1670), the active metabolite of the widely used antipsoriatic drug etretinate (Ro 10-9359), on the incorporation and release of arachidonic acid in human skin keratinocytes. During 24-h culture, radioactive 14C-arachidonic acid was avidly incorporated int