The effect of rapamycin on bone growth i
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Chanika Phornphutkul; Mark Lee; Cliff Voigt; Ke-Ying Wu; Michael G. Ehrlich; Phi
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Article
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2009
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Elsevier Science
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English
β 197 KB
π 1 views
## Abstract mTOR is a nutrientβsensing protein kinase that regulates numerous cellular processes. Our prior studies using the mTOR inhibitor, rapamycin, indicate an important role for mTOR in chondrogenesis. We extended our observations to a physiological, in vivo model of bone growth, direct infus