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The effect of surface modification on the stability characteristics of poly(N-isopropylacrylamide) latices under Brownian and flow conditions

✍ Scribed by M. J. Snowden; N. J. Marston; B. Vincent

Publisher
Springer
Year
1994
Weight
620 KB
Volume
272
Category
Article
ISSN
0340-255X

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## Abstract Covalent modification of purified __Trigonopsis variabilis__ D‐amino acid oxidase using maleimide‐activated poly(ethylene glycol) 5000 yielded a stable bioconjugate in which three surface‐exposed cysteine side chains were selectively derivatized. Compared with the native enzyme, the PEG