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The effect of sulfation on the anticoagulant and antithrombin III-binding properties of a heparin fraction with low affinity for antithrombin III

✍ Scribed by Pieter Schoen; Simone Wielders; Maurice Petitou; Theo Lindhout


Book ID
119037818
Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
607 KB
Volume
57
Category
Article
ISSN
0049-3848

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An objective of this research is to verify the mechanism of anticoagulant activity of surface-immobilized heparin in the presence of plasma proteins. The competition and binding interaction between immobilized heparin and antithrombin I11 (ATIII)/thrombin have been described in vituo. However, the s