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The Effect of Sulfasalazine and Its Active Components on Human Polymorphonuclear Leukocyte Function in Relation to Ulcerative Colitis

✍ Scribed by Molin, Lars ;Stendahl, Olle


Book ID
114692070
Publisher
Wiley (Blackwell Publishing)
Year
2009
Weight
601 KB
Volume
206
Category
Article
ISSN
0001-6101

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Hypothesis about mechanisms through whic
✍ Victoria E. McGilligan; Julie M. W. Wallace; Patricia M. Heavey; Diana L. Ridley πŸ“‚ Article πŸ“… 2007 πŸ› John Wiley and Sons 🌐 English βš– 105 KB

Ulcerative colitis (UC) is characterized by impairment of the epithelial barrier and the formation of ulcer-type lesions, which result in local leaks and generalized alterations of mucosal tight junctions. Ultimately, this results in increased basal permeability. Although disruption of the epithelia