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The effect of solutes and polymers on the gelation properties of pluronic F-127 solutions for controlled drug delivery

✍ Scribed by Julian C. Gilbert; Julie L. Richardson; Martyn C. Davies; Karen J. Palin; Jonathan Hadgraft

Book ID
119133593
Publisher
Elsevier Science
Year
1987
Tongue
English
Weight
507 KB
Volume
5
Category
Article
ISSN
0168-3659

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We have examined the effect of NaCl, Na 2 SO 4 , Na 3 PO 4 , and NaSCN on F127 solutions; properties examined were critical micellization temperature (cmt), cloud point, and solubilization of a model hydrophobic drug, propyl paraben. Static light scattering showed that the first three salts lower th