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The effect of small interfering RNA (siRNA) against the Bcl-2 gene on apoptosis and chemosensitivity in a canine mammary gland tumor cell line

✍ Scribed by Kota Nagamatsu; Fumito Tsuchiya; Keisuke Oguma; Haruhiko Maruyama; Rui Kano; Atsuhiko Hasegawa

Book ID: 116874377
Publisher: Elsevier Science
Year: 2008
Tongue: English
Weight: 409 KB
Volume: 84
Category: Article
ISSN: 0034-5288
DOI: 10.1016/j.rvsc.2007.03.012

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## Abstract Silencing of a specific mRNA using double stranded RNA oligonucleotides represents one of the newest technologies for suppressing a specific gene product. Small interfering RNA (siRNA) are 21 nucleotides long, double stranded RNA fragments that are identical in sequence to the target mR