𝔖 Bobbio Scriptorium
✦   LIBER   ✦

The Effect of Single versus Double-Strand Substitution on Halogenated Pyrimidine-Induced Radiosensitization and DNA Strand Breakage in Human Tumor Cells

✍ Scribed by Theodore S. Lawrence, Mary A. Davis, Jonathan Maybaum, Philip L. Stetson and William D. Ensminger

Book ID
124692178
Publisher
Bioone
Year
1990
Tongue
English
Weight
378 KB
Volume
123
Category
Article
ISSN
0033-7587

No coin nor oath required. For personal study only.

πŸ“œ SIMILAR VOLUMES

Relationship between the radiosensitizin
Relationship between the radiosensitizing effect of wortmannin, DNA double-strand break rejoining, and p21WAF1 induction in human normal and tumor-derived cells
✍ Razmik Mirzayans; Scott Pollock; April Scott; Louise Enns; Bonnie Andrais; David πŸ“‚ Article πŸ“… 2004 πŸ› John Wiley and Sons 🌐 English βš– 219 KB

## Abstract Wortmannin (WM) is a potent inhibitor of the catalytic sub‐unit of DNA‐PK, which is involved in one pathway of DNA double‐strand break (DSB) rejoining, and of ATM, which functions upstream in the p53 signaling pathway. WM is known to be an efficient radiosensitizer in a variety of mamma