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The effect of single oral doses of zopiclone on nocturnal melatonin secretion in healthy male volunteers

โœ Scribed by Trevor R Norman; Josephine Piccolo; Nicholas Voudouris; Graham D Burrows


Book ID
117448816
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
332 KB
Volume
25
Category
Article
ISSN
0278-5846

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The pharmacokinetics and tolerability of a new putative non-benzodiazepine type anxiolytic compound deramciclane was studied in two consecutive studies. An open dose-escalation design was used to study doses from 0.2 to 50 mg in 18 healthy male volunteers. In the second study doses from 50 to 150 mg