The effect of short-term and prolonged fructose intake on VLDL-TG and relative properties on apo CIII1 and apo CII in the VLDL fraction in type IV hyperlipoproteinaemia
✍ Scribed by Cybulska, B. ;Naruszewicz, M.
- Publisher
- John Wiley and Sons
- Year
- 1982
- Tongue
- English
- Weight
- 489 KB
- Volume
- 26
- Category
- Article
- ISSN
- 0027-769X
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✦ Synopsis
Abstract
Twenty two patients with hyperlipoproteinaemia type IV consumed fructose in a daily dose of 80 g for 28 days. Apart from that they kept their normal diet. We observed the considerable heterogeneity of hyperlipaemic responses of patients under study after 7 days of fructose feeding. However VLDL‐TG and the relative ratio apo CIII~1~/apo CII in VLDL increased in the whole group. The rise in serum VLDL was associated with a fall in LDL‐Chol and HDL‐Chol.
After extention of fructose intake to 28 days a decrease of VLDL‐TG with concomitant fall of the relative ratio apo CIII~1~/apo CII in VLDL was found. LDL‐Chol increased.
Our observations point to the reversibility of fructose‐induced changes in the lipoprotein composition after prolongation of its intake.