The effect of shielding the hepatic area on the clinical response to phototherapy
โ Scribed by Thomas Hegyi; Vernessa Brantley; I. Mark Hiatt
- Book ID
- 104776372
- Publisher
- Springer
- Year
- 1981
- Tongue
- English
- Weight
- 240 KB
- Volume
- 137
- Category
- Article
- ISSN
- 0340-6997
No coin nor oath required. For personal study only.
โฆ Synopsis
The changes in serum bilirubin concentration in response to phototherapy were studied in 26 infants with and without an opaque patch on the liver area. Fifteen infants in the patched group were treated at a mean age of 50.7 h, and 11 control infants at 49.1 h. No significant differences were demonstrated between the two groups in duration ofphototherapy, peak bilirubin concentration and rates of bilirubin decrement.
Shielding the hepatic area during illumination does not alter the clinical response to phototherapy which suggests that the main site of action of phototherapy is in the skin.
๐ SIMILAR VOLUMES
Jaundiced Gunn rats, treated with phenobarbital (60 mg per kg i.p. for 7 to 10 days) showed 25 and 36% decreases in mean plasma bilirubin levels in two experiments (p < 0.01). Kinetic studies with tracer 14C-bilirubin revealed that there was no change in bilirubin turnover or total pool size due to