The effect of shear stress on the basolateral membrane potential of proximal convoluted tubule of the rat kidney
โ Scribed by Mariano L. Lopardo; Paula Diaz-Sylvester; Carlos Amorena
- Publisher
- Springer
- Year
- 2007
- Tongue
- English
- Weight
- 206 KB
- Volume
- 454
- Category
- Article
- ISSN
- 0031-6768
No coin nor oath required. For personal study only.
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The effects of glucagon on water and electrolyte transport in the kidney were investigated on hormonedeprived rats, i.e. thyroparathyroidectomized diabetes insipidus Brattleboro rats infused with somatostatin. Glucagon consistently inhibited the reabsorption of water and Na +, CI-, K ยง and Ca 2 ยง al
The membrane potential of proximal tubule cells is dominated by the potassium conductance of the basolateral membrane. In the present paper the nature of this conductance is investigated by the patch-clamp technique. Only one type of K channel was found in the basolateral membranes of freshly isolat