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The effect of secondhand smoke exposure on the association between active cigarette smoking and colorectal cancer

โœ Scribed by Luke J. Peppone; Mary E. Reid; Kirsten B. Moysich; Gary R. Morrow; Pascal Jean-Pierre; Supriya G. Mohile; Tom V. Darling; Andrew Hyland


Publisher
Springer Netherlands
Year
2010
Tongue
English
Weight
251 KB
Volume
21
Category
Article
ISSN
0957-5243

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## Abstract Cigarette smoke contains polycyclic hydrocarbons and arylamines that may both be activated by sulfotransferase, encoded by __SULT1A1__. A genetic polymorphism leads to an Arg213His substitution, thereby decreasing enzyme activity and stability and might thus modify the association betwe