The effect of propylene glycol on the antibiotic activity of human serum
β Scribed by Samuel J. Prigal; Thomas H. McGavack; Mary Bell
- Book ID
- 118831989
- Publisher
- Elsevier Science
- Year
- 1947
- Tongue
- English
- Weight
- 281 KB
- Volume
- 3
- Category
- Article
- ISSN
- 1555-7162
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π SIMILAR VOLUMES
The objective was to assess the impact of propylene glycol (PG), a common cosolvent in topical formulations, on the penetration of ibuprofen into human skin in vivo. Drug uptake into the stratum corneum (SC), following application of saturated formulations containing from 0 to 100% v/v PG, was asses
## Abstract ## Purpose To establish the bloodβbrain barrier (BBB) blocking property of propylene glycol (PG) using the ^14^C sucrose technique, quantitatively evaluate the effect of PG on BBB permeability using an MRI technique based on graphical analysis, and demonstrate the sensitivity of MRI fo