Effect of indomethacin on the pharmacoki
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Tawfeeg A. O. Najjar; Abdel Rehim M. Morad; Rao Muzaffar A. Khan
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Article
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1992
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John Wiley and Sons
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English
β 300 KB
π 3 views
## Abstract The interaction between indomethacin (IND) and methotrexate (MTX) was investigated in rabbits. The study was designed so as to evaluate the effect of IND (1 mg h^β1^) during a continuous MTX infusion (1Β·2 mg kg^β1^) over 240 min. IND was injected i.v. at hourly intervals after a steady