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The effect of previous exposure to amphetamine on drug-induced locomotion and self-administration of a low dose of the drug

✍ Scribed by P. Vezina; P. J. Pierre; D. S. Lorrain

Publisher
Springer
Year
1999
Tongue
English
Weight
88 KB
Volume
147
Category
Article
ISSN
0033-3158

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## Abstract Levodopa (L‐dopa) consistently primes basal ganglia for the appearance of dyskinesia in parkinsonian patients and 1‐methyl‐4‐phenyl‐1,2,3,6‐tetrahydropyridine hydrochloride (MPTP) ‐treated primates. This finding may reflect its relatively short duration of effects resulting in pulsatile