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The effect of polyinosinic: Polycytidylic acid on fluorescent and neutralizing antibodies to herpesvirus saimiri in goats

✍ Scribed by C. E. O. Fraser; L. V. Meléndez; H. H. Barahona; M. D. Daniel


Publisher
John Wiley and Sons
Year
1971
Tongue
French
Weight
398 KB
Volume
7
Category
Article
ISSN
0020-7136

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✦ Synopsis


Abstract

Goats are the best species so far tested for the preparation of fluorescent and neutralizing antibodies to Herpesvirus saimiri. Fluorescent antibodies to Herpesvirus saimiri seem to be different to neutralizing antibodies and polyinosinic: polycytidylic acid (poly I: C) may be of value in separating these two activities.

Primary response fluorescent antibodies stained infected monolayers in a characteristic pattern, which is different from that of secondary response antibodies. The immunological and epidemiological implications of this are discussed.