Interspecies differences in the effect o
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D. R. Rutledge; M.-T. Chong; M. V. Nelson
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Article
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1991
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Springer
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English
โ 432 KB
There is little information about the factors which influence drug protein binding between species. We have therefore investigated the role of pH on the binding of gallopamil, a calcium channel antagonist known to exhibit pH-sensitive binding, among four species, human, baboon, bovine, and canine. W