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The effect of pergolide and MDL 72974 on rat brain CuZn superoxide dismutase

โœ Scribed by Clow, Angela; Freestone, Clare; Lewis, Emma; Dexter, David; Sandler, Merton; Glover, Vivette


Book ID
122705080
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
267 KB
Volume
164
Category
Article
ISSN
0304-3940

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MDL72974 is a member of a series of MAO-B inhibitors to be used as potential therapeutic agents in the treatment of Parkinson's and Alzheimer's diseases. However, we have recently observed a reduction in the density of tyrosine hydroxylase (TH)-positive neurons in the substantia nigra of mice treate