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The effect of particle size and charge on the clearance rates of liposomes and liposome encapsulated drugs

✍ Scribed by R.L. Juliano; D. Stamp

Book ID
119406080
Publisher
Elsevier Science
Year
1975
Tongue
English
Weight
384 KB
Volume
63
Category
Article
ISSN
0006-291X

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The pharmacokinetics of 3H-Triamcinolone Acetonide-21-palmitate entrapped in liposomes with neutral, negative and positive surface charge was investigated in the male New Zealand White rabbit after a single intravenous bolus injection. Drug concentration-time data monitored in whole blood showed bi-