The effect of papain, pronase, Nagarse and trypsin on isolated amyloid fibrils
β Scribed by In Chang Kim; Carl Franzblau; Tsuranobu Shirahama; Alan S. Cohen
- Book ID
- 115748437
- Publisher
- Elsevier Science
- Year
- 1969
- Weight
- 191 KB
- Volume
- 181
- Category
- Article
- ISSN
- 0005-2795
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## Abstract Macromolecular crowding is expected to have several significant effects on protein aggregation; the major effects will be those due to excluded volume and increased viscosity. In this report we summarize data demonstrating that macromolecular crowding may lead to a dramatic acceleration
## Abstract Amyloid fibrils are selfβassociating filamentous structures deposited in extracellular tissue in various neurodegenerative and protein misfolding disorders. It has been shown that betaβsheetβbreaker (BSB) peptides may interfere with amyloid fibril assembly. Although BSB peptides are pro