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The effect of paclitaxel on 2-aminofluorene–DNA adducts formation and arylamine N-acetyltransferase activity and gene expression in human lung tumor cells (A549)

✍ Scribed by T.C Hsia; J.G Chung; H.F Lu; H.C Ho; C.C Yang; K.H Lu; C.F Hung

Book ID: 117449934
Publisher: Elsevier Science
Year: 2002
Tongue: English
Weight: 170 KB
Volume: 40
Category: Article
ISSN: 0278-6915
DOI: 10.1016/s0278-6915(01)00128-4

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## Abstract In this study, butylated hydroxyanisole (BHA) and butylated hydroxytoluene (BHT) were used to determine the inhibition of arylamine __N__‐acetyltransferase (NAT) activity and DNA adduct formation in human bladder tumour cell line T‐24. The activity of NAT was measured by high‐performanc