Effect of apolipoprotein AII on the inte
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Kazuyoshi Yamauchi; Minoru Tozuka; Hiroya Hidaka; Tetsuo Nakabayashi; Mitsutoshi
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Article
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2000
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John Wiley and Sons
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English
⚖ 115 KB
👁 1 views
Apolipoprotein (apo) E and its polymorphism are linked to the pathogenesis of late-onset and sporadic Alzheimer's disease (AD). ApoE facilitates the deposition and fibrillogenesis of beta-amyloid (Abeta), and may participate in Abeta clearance. We recently found that apo(E-AII) complex binds to Abet