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The effect of oral clarithromycin on health status and sputum bacteriology in stable COPD

โœ Scribed by D. Banerjee; O.A. Khair; D. Honeybourne

Book ID
116871135
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
198 KB
Volume
99
Category
Article
ISSN
0954-6111

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Sildenafil is the first oral therapeutic agent for the management of male erectile dysfunction. Its oral bioavailability is only 40% due to extensive presystemic elimination, mainly by CYP3A4. This study examined the effect of coadministration of ciprofloxacin or clarithromycin, which inhibit CYP3A4