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The effect of non-steroidal anti-inflammatory drugs andHelicobacter pyloriinfection on the gastric mucosa in children with upper gastrointestinal bleeding

✍ Scribed by Samir Boukthir; Sonia M. Mazigh; Nicolas Kaach; Olfa Bouyahya; Azza Sammoud

Publisher: Springer-Verlag
Year: 2009
Tongue: English
Weight: 158 KB
Volume: 26
Category: Article
ISSN: 0179-0358
DOI: 10.1007/s00383-009-2492-x

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The effects of non-steroidal anti-inflammatory drugs on the disposition of methotrexate in patients with rheumatoid arthritis

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We have studied the pharmacokinetics of methotrexate in patients with rheumatoid arthritis concurrently taking the most commonly used non-steroidal anti-inflammatory drugs (NSAIDs), aspirin, diclofenac, naproxen, indomethacin, and ibuprofen. The area under the curve, the total systemic clearance, t