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The effect of neuroleptics on imipramine demethylation in rat liver microsomes and imipramine and desipramine level in the rat brain

✍ Scribed by Władysława Daniel; Mirosława Melzacka


Book ID
115779050
Publisher
Elsevier Science
Year
1986
Tongue
English
Weight
539 KB
Volume
35
Category
Article
ISSN
0006-2952

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The influence of orally administered activated charcoal on organ concentrations of parenteral imipramine and desipramine was investigated. Ancillary distribution experiments indicated that the gastroenteral cycle of these substances might be more important than the enterohepatic cycle. Nevertheless