✦ LIBER ✦

The effect of N-alkyl groups of substituted phenyl-N alkyl carbamates on the inhibition of human plasma cholinesterase

✍ Scribed by G. Voss

Publisher: Springer-Verlag
Year: 1976
Tongue: English
Weight: 205 KB
Volume: 36
Category: Article
ISSN: 0340-5761
DOI: 10.1007/bf00351970

No coin nor oath required. For personal study only.

✦ Synopsis

The inhibition constants for human plasma cholinesterase (dissociation, carbamylation, decarbamylation, overall bimolecular rate constants) were determined for two series of substituted phenyl-N-alkyl carbamates. N-propyl carbamates were found to be better inhibitors than the corresponding compounds carrying smaller N-alkyl groups. In both series the carbamylation constants of N-ethyl carbamates were lower than those of the N-methyl and N-propyl analogues, whereas the decarbamylation constants of the former were found to be higher than those of the latter carbamates. The experimental results obtained with human plasma cholinesterase are compared with published inhibition constants determined for several types of acetylcholinesterases.

📜 SIMILAR VOLUMES

The gear effect, II : The conformation o

The gear effect, II : The conformation of the N-alkyl groups in N,N′-diisopropyl thioacetamide

✍ C. Roussel; M. Chanon; J. Metzger 📂 Article 📅 1972 🏛 Elsevier Science 🌐 French ⚖ 179 KB

The effect of alkyl groups on the electr

The effect of alkyl groups on the electronic spectra of benzenoid hydrocarbons

✍ Edgar Heilbronner; John N. Murrell 📂 Article 📅 1963 🏛 Springer 🌐 English ⚖ 601 KB

Hammett–Taft cross-interaction correlati

Hammett–Taft cross-interaction correlations for the inhibition mechanism of cholesterol esterase by substituted phenyl N-substituted carbamates

✍ Gialih Lin 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 English ⚖ 135 KB

Effect of the alkyl chlorsilanes on the

Effect of the alkyl chlorsilanes on the N-vinyl pyrrolidone polymerization

✍ George S. Georgiev; Vitaly P. Zubov 📂 Article 📅 1980 🏛 Springer 🌐 English ⚖ 153 KB

Effects of the substituents on radical p

Effects of the substituents on radical polymerization kinetics of n-(alkyl-substituted phenyl)maleimides initiated with dimethyl 2,2′-azobisisobutyrate

✍ Akikazu Matsumoto; Yoshitaka Oki; Takayuki Otsu 📂 Article 📅 1993 🏛 Elsevier Science 🌐 English ⚖ 391 KB

Alternating copolymerization of N-(alkyl

Alternating copolymerization of N-(alkyl-substituted phenyl)maleimides with isobutene and thermal properties of the resulting copolymers

✍ Toru Doi; Akira Akimoto; Akikazu Matsumoto; Yoshitaka Oki; Takayuki Otsu 📂 Article 📅 1996 🏛 John Wiley and Sons 🌐 English ⚖ 522 KB

Radical copolymerization of N-(alkyl-substituted pheny1)maleimides (RPhMI) with isobutene (IB) was carried out with an initiator in various solvents at 6OoC. The copolymerization of N-(2,6-diethylphenyl)maleimide (2,6-DEPhMI) with IB in benzene proceeded readily in a homogeneous system to give an al