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The effect of myocardial fibrosis on ventricular remodeling following valve replacement for severe aortic stenosis. A CMR study comparing transcatheter aortic valve implantation and surgical aortic valve replacement

✍ Scribed by Timothy Fairbairn; Christopher D Steadman; Adam N Mather; Manish Motwani; Daniel Blackman; Sven Plein; Gerry P McCann; John P Greenwood


Publisher
BioMed Central
Year
2012
Tongue
English
Weight
197 KB
Volume
14
Category
Article
ISSN
1097-6647

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✦ Synopsis


Myocardial fibrosis (MF) that occurs in aortic stenosis (AS) has been shown to be associated with a poor prognostic outcome post surgical aortic valve replacement (SAVR) but not in the high risk patients suitable for Transcatheter aortic valve implantation (TAVI). Using the technique of late-gadolinium enhancement we have shown that MF regresses post-TAVI but not post-SAVR, and that ejection fraction rather than MF is the independent predictor of reverse remodeling.