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The Effect of Mobile Phase on Protein Retention and Recovery Using Carboxymethyl Dextran-Coated Zirconia Stationary Phases

โœ Scribed by Dunlap, C. J.; Carr, P. W.

Book ID
126705620
Publisher
Taylor and Francis Group
Year
1996
Tongue
English
Weight
749 KB
Volume
19
Category
Article
ISSN
1082-6076

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## Abstract Hydrophobic interaction chromatography (HIC) is known to be potentially denaturing to proteins, but the effects of mobile phase conditions on chromatographic behavior are not well understood. In this study, we apply a model describing the effects of secondary protein unfolding equilibri