✦ LIBER ✦

The effect of microwave radiation on the stability and formation of gramicidin-A channels in lipid bilayer membranes

✍ Scribed by John Sandblom; Sten Theander

Publisher: John Wiley and Sons
Year: 1991
Tongue: English
Weight: 634 KB
Volume: 12
Category: Article
ISSN: 0197-8462
DOI: 10.1002/bem.2250120103

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✦ Synopsis

The effects of microwaves on the single-channel kinetics of gramicidin-A channels in lipid bilayer membranes were examined. Attempts were made to separate thermal and athermal effects by accurate measurements of temperature at the site of the membrane and by relating the measured parameters to their previously characterized temperature dependence. It was found that microwave radiation does not affect single-channel conductance or channel life time to a degree that is significantly different from that expected of a purely thermal effect. On the other hand, the rate of channel formation is decreased during exposure, which is opposite to that expected of a purely thermal effect. The mechanism of this effect is discussed in terms of the dimeriration process of channel formation.

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