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The effect of margins on the clinical management of ductal carcinoma in situ of the breast

โœ Scribed by Philip Meijnen; Kenneth G. Gilhuijs; Emiel J.Th. Rutgers


Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
102 KB
Volume
98
Category
Article
ISSN
0022-4790

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## Background: More than 50% of breast ductal carcinomas in situ (dcis) contain significant histologic necrosis, an important prognostic factor for determining recurrence and progression to invasive breast cancer. we have examined whether the mechanism of this spontaneous cell death might be apopto