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The effect of lithium administration on LH response in healthy volunteers

✍ Scribed by Grof, Eva; Brown, Gregory M.; Grof, Paul; Saxena, Bishan


Book ID
122559626
Publisher
Elsevier Science
Year
1988
Tongue
English
Weight
319 KB
Volume
12
Category
Article
ISSN
0278-5846

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The phosphoinositide (PI) cycle second messenger system mediates the effect of muscarinic receptor binding. Inositol, which is an essential substrate for phosphoinositide synthesis penetrates the blood-brain barrier poorly, and is vulnerable to depletion. Lithium uncompetitively inhibits inositol-1