The effect of liposome (phospholipid vesicle) entrapment of actinomycin D and methotrexate on the in vivo treatment of sensitive and resistant solid murine tumours
β Scribed by S.B. Kaye; Joan A. Boden; Brenda E. Ryman
- Book ID
- 113146681
- Publisher
- Elsevier Science
- Year
- 1981
- Weight
- 853 KB
- Volume
- 17
- Category
- Article
- ISSN
- 0014-2964
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
Annamycin (Ann) is a non-cross-resistant lipophilic anthracycline antibiotic optimally suited for liposome delivery. We studied how vesicle size and presence of phospholipids with a high phase transition temperature and monosialoganglioside (GM I) in the liposome bilayers affect the pharmacokinetics
Interferon-gamma (IFN-y) treatment or in vivo passage of the murine YAC-I lymphoma resulted in reduced sensitivity to in vitro lysis by syngeneic murine spleen cells cultured in rll-2 (LAK-cells). IFN-y treatment also rendered the murine B16 melanoma less sensitive to lysis by syngeneic LAK cells, w