The effect of leptin on Na+-H+ antiport (NHE 1) activity of obese and normal subjects erythrocytes
โ Scribed by A Konstantinou-Tegou; M Kaloyianni; D Bourikas; G Koliakos
- Book ID
- 117462897
- Publisher
- Elsevier Science
- Year
- 2001
- Tongue
- English
- Weight
- 138 KB
- Volume
- 183
- Category
- Article
- ISSN
- 0303-7207
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Kinetic properties of the Na(+)-H+ antiport in the acinar cells of the isolated, superfused mouse lacrimal gland were studied by measuring intracellular pH (pHi) and Na+ activity (aNai) with the aid of double-barreled H(+)- and Na(+)-selective microelectrodes, respectively. Bicarbonate-free solution
It is uncertain why only one third of Type 1 (insulin-dependent) diabetic patients develop nephropathy. One suggestion is the inheritance of a predisposition to essential hypertension. We have previously found elevated Na+/H+ antiport activity and a raised intracellular pH in leucocytes from hyperte