The effect of lentinan on production of interleukin-1 by human monocytes
β Scribed by John P. Fruehauf; Guy D. Bonnard; Ronald B. Herberman
- Publisher
- Elsevier Science
- Year
- 1982
- Tongue
- English
- Weight
- 591 KB
- Volume
- 5
- Category
- Article
- ISSN
- 0162-3109
No coin nor oath required. For personal study only.
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The constitutive and lipopolysaccharide (LPS)-induced secretion of interleukin 1 (IL 1) by cultured human monocytes and macrophages has been studied. Both freshly obtained monocytes and their culture-derived macrophages were induced by LPS to secrete similar amounts of IL 1. Such induction, however,
## Abstract When monocytes are activated with endotoxin (lipopolysaccharide [LPS]), they make and release several mediators, including interleukinβ1Ξ² (ILβ1Ξ²). This study was undertaken to investigate the role of glucose in ILβ1Ξ² production by these cells. ILβ1Ξ² was produced in a doseβdependent mann