The effect of lentinan on macrophage cytotoxicity against metastatic tumor cells
✍ Scribed by A. Ladányi; Lapis K.
- Publisher
- Elsevier Science
- Year
- 1991
- Tongue
- English
- Weight
- 83 KB
- Volume
- 13
- Category
- Article
- ISSN
- 0192-0561
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract The present study has examined the competence of peritoneal cells (PC) of tumor bearers to reverse the immunosuppressive effect of tumor cells, and the ability of the tumor bearers to generate a T‐cell‐mediated cytotoxic response against allogeneic spleen cells or allogeneic tumor cells
Histological examination of the metastatic rat mammary adenocarcinoma line MTLn3 showed that macrophages and mast cells were frequently localized at the tumor periphery in the stromal tissues adjacent to the zones of tumor invasion. The interactions of these host cells with tumor cells and tumor-ass
O6-Alkylguanine derivatives are well known as chemical modulators of the DNA repair enzyme O6-methylguanine-DNA methyltransferase (MGMT). Depletion of the enzyme by these derivatives leads to increase sensitivity of tumor cells to chloroethylnitrosoureas. We tested the effect of O6-methylguanine, O6