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The Effect of Isoniazid on the Clearance of Pyruvic and α-Oxoglutaric Acids in the Urine of Mice, Meriones lybicus and Rats

✍ Scribed by Chalmers, J G


Book ID
109832999
Publisher
Nature Publishing Group
Year
1965
Tongue
English
Weight
288 KB
Volume
19
Category
Article
ISSN
0007-0920

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Tuberculosis chemotherapy involves combination of the drugs isoniazid (INH), rifampicin (RMP) and pyrazinamide (PYR) for a 6-month period. The present work investigated the influence of RMP and PYR on the pharmacokinetic parameters of INH when groups of rats were pre-treated for 21 days with INH alo