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The effect of isolancifolide on the apoptosis in HL-60 cells through caspase-8-dependent and -independent pathways

✍ Scribed by Jeong June Choi; Ok-Kyoung Kwon; Sei-Ryang Oh; Hyeong-Kyu Lee; Kyung-Seop Ahn

Book ID: 113100880
Publisher: Springer
Year: 2012
Tongue: English
Weight: 799 KB
Volume: 35
Category: Article
ISSN: 0253-6269
DOI: 10.1007/s12272-012-0115-x

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## Abstract Thymoquinone (TQ), the major biologically active component isolated from a traditional medicinal herb, __Nigella sativa__ Linn, is a potential chemopreventive and chemotherapeutic compound. Despite the promising antineoplastic activities of TQ, the molecular mechanism of its pharmacolog